aZLBI0121c Biologie I - cvičení

Lékařská fakulta
podzim 2026
Rozsah
0/2/0. 30. 2 kr. Ukončení: z.
Vyučováno kontaktně
Vyučující
prof. RNDr. Ondřej Slabý, Ph.D. (přednášející)
prof. MUDr. Iva Slaninová, Ph.D. (přednášející)
Ing. Lívia Eiselleová, Ph.D. (cvičící)
Mgr. Kateřina Cetkovská, Ph.D. (cvičící)
Mgr. Kateřina Francová, Ph.D. (cvičící)
Mgr. Kateřina Kučerová, Ph.D. (cvičící)
Jana Růžičková (pomocník)
Mgr. Kateřina Vopěnková, Ph.D. (cvičící)
Mgr. Petra Pospíšilová, Ph.D. (cvičící)
Mgr. Kateřina Holubová (cvičící)
Mgr. Lenka Bešše, Ph.D. (cvičící)
Mgr. Andrej Bešše, Dr. sc. nat. (cvičící)
MUDr. Martin Pešl, Ph.D. (cvičící)
Mgr. Marek Večeřa, Ph.D. (cvičící)
Mgr. Viktor Kostohryz (cvičící)
Mgr. Jana Vepřková (cvičící)
Mgr. Kateřina Koždoňová (cvičící)
Mgr. František Siegl (cvičící)
Mgr. Barbora Valčíková (cvičící)
Ing. Natália Vadovičová (cvičící)
Mgr. Nikola Kaštánková (cvičící)
Mgr. Anna Lešková (cvičící)
Mgr. Lucia Knapeková (cvičící)
Garance
prof. MUDr. Iva Slaninová, Ph.D.
Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Kontaktní osoba: Ing. Lívia Eiselleová, Ph.D.
Dodavatelské pracoviště: Biologický ústav – Teoretická pracoviště – Lékařská fakulta
Rozvrh seminárních/paralelních skupin
aZLBI0121c/40: St 14:30–15:00 B07/205a, St 15:00–16:00 B07/205a, St 15:00–16:00 B07/217, St 16:00–16:10 B07/205a
aZLBI0121c/41: St 7:30–8:00 B07/205a, St 8:00–9:00 B07/217, St 8:00–9:00 B07/205a, St 9:00–9:10 B07/205a
Předpoklady
Knowledge of high-school biology on the level of Overview of High School Biology (https://is.muni.cz/auth/do/med/el/overview/overview_ENG.qwarp) or similar is required.
Omezení zápisu do předmětu
Předmět je určen pouze studentům mateřských oborů.
Mateřské obory/plány
Anotace
The main objectives of the course are:
- learning to operate the light microscope while observing prokaryotic and eukaryotic cells and various cell structures and processes
- understanding the methodology of assembling and examining the karyotype (evaluation of basic numerical and structural aberrations)
- evaluate the risk of numerical and structural aberrations resulting from meiotic non-disjunction and chromosomal translocations
- use some of the basic techniques of molecular biology to monitor the cell cycle and cell death
- describe the stages of cell division
Výstupy z učení
After completing the course, the student will be able to:
- operate the light microscope
- perform some of the basic cytochemical staining techniques in observation of bacterial and human cells
- explain the basic principles and use of electron microscopy
- describe the basic techniques and applications of tissue and cell cultures
- deduce the impact of selected DNA mutations on the primary structure of proteins
- explain the methodology of assembling and examining the karyotype and its use, and evaluate basic numerical and structural aberrations in assigned human karyotypes
- evaluate the risk of numerical and structural aberrations resulting from meiotic non-disjunction and chromosomal translocations
Klíčová témata
    • Week 1: Instructions. Non-cellular organisms and infectious agents
    • Week 2: Prokaryotic cells, basics of light microscopy
    • Week 3: Microscopic observation of eukaryotic cells
    • Week 4: In vitro culture of human cells
    • Week 5: Principles of electron microscopy and cellular ultrastructure
    • Week 6: Study of DNA damage
    • Week 7: DNA structure, DNA replication, gene expression
    • Week 8: Human karyotype and chromosomal aberrations
    • Week 9:  Basic methods of Molecular Biology I. 
    • Week 10: Mitosis and meiosis observation under a light microscope
    • Week 11: Methods for studying cell cycle
    • Week 12: Methods for studying cell death
    • Week 13: Control test from week 12 + microscopic exam
    • Week 14: no practice - dissection week, credit awarding
Studijní zdroje a literatura
    povinná literatura
  • Actual protocols for practices are provided in electronic form in the Information System of the Masaryk University (IS): Study Materials of the course aZLBI0121c
Přístupy, postupy a metody používané ve výuce
laboratory practice, class discussion
Způsob ověření výstupů z učení a požadavky na ukončení
Requirements for course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and submitted to the Home Vaults; successful passing of all the tests throughout the semester; and passing the microscopy exam.  Students must earn at least 60 points (out of a total 100) on all tests for the semester.  If students fail the control tests (less than 60 points in total), they will write the Credit test (15 test questions, 5 terms for a written explanation). 
In case of a student’s late arrival to the practice or poor activity at the practice, the student must write an essay of 2 pages on a given topic. Same for the case of 2nd and any additional absence in practices (excused or unexcused). Find the instructions for essay writing in the Course-related instructions in the IS.
In case of 3 absences (or more than 3 absences, all excused by the Office for Studies within five days from the beginning of the absence and introduced to the Information System), it is addressed individually.
Course-unit credit is not awarded in case of 4 or more unexcused absences.

Vyučovací jazyk
Angličtina
Navazující předměty
Odkaz a informace vyučujících
https://is.muni.cz/auth/el/med/podzim2026/aZLBI0121c/index.qwarp
Interactive syllabus of the course:
https://is.muni.cz/auth/el/med/podzim2026/aZLBI0121c/index.qwarp
What to bring to each practice: printed or downloaded protocol for the respective practice and your own writing materials. Download the protocol for each practice from the Study materials or Interactive syllabus in the IS and study it in advance. Lab shoes/slippers are required; lab coats and disposable gloves are not required.
Substitution of practices: In exceptional cases (illness, appointment at the doctor or foreign policy, once or two times per semester at most), a student can arrange a substitution with another group. To arrange a substitution, write an e-mail to the contact person at least 24 hours before your planned substitution and specify the group (date and time) you would like to attend instead (see Interactive syllabus - Instructions for the course - Timetable). Substitution is only possible on the same teaching week. When the capacity of the group you intend to substitute with is fully used, the substitution does not need to be approved. Repeated substitution with other groups is not allowed.
Complete Biology instructions are to be found in the Interactive syllabus of the course.
Další komentáře
Předmět je vyučován každoročně.
Nachází se v prerekvizitách jiných předmětů
Předmět je zařazen také v obdobích podzim 2015, podzim 2016, podzim 2017, podzim 2018, podzim 2019, podzim 2020, podzim 2021, podzim 2022, podzim 2023, podzim 2024, podzim 2025.
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